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Preheat oven to 200°C. Season tilapia with salt, pepper, paprika, thyme, and oregano; arrange fish in a 9×13 baking dish.
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In a mixing bowl, whisk together melted butter, garlic, lemon juice, and lemon zest; pour over tilapia.
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Bake tilapia for 10 to 12 minutes, or until fish flakes and is fork-tender.
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Garnish with pepper flakes, parsley, and lemon slices. Serve.